An Attractive Strategy for Enhanced Therapeutic Profile: Self-Microemulsifying Drug Delivery System for Oral Bioavailability Enhancement

Hanmant S. Mali1*, Safiya R. Shaikh2, Akshay R. Yadav3, Indrayani D. Raut4, Mangesh A. Bhutkar5, Shrinivas K. Mohite6, Chandrakant S. Magdum7 1,4,5Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon, Dist-Sangli, Maharashtra, India-415404 2,3,6,7Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Dist-Sangli, Maharashtra, India-415404    ABSTRACT SEDDS are used to poorly soluble, highly permeable, and

Molecular Docking Studies of Novel Tetrasubstituted Thiophene Analogues against SARS-CoV-2 Inhibitors for COVID-19

Akshay R. Yadav* & Prashant S. Salunkhe Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Dist- Sangli, Maharashtra, India-415404    ABSTRACT The knowledge of various synthetic pathways and the diverse physicochemical parameters of such compounds draw the especial attention of medicinal chemists to produce combinatorial library and carry out exhaustive efforts in the search

Molecular Docking Studies of Phytoconstituents Identified in Acorus calamus Linn. on HMG-CoA reducatse- An Enzyme Target for Antihyperlipidemic Activity

Akshay R. Yadav* & Prashant S. Salunkhe Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Dist-Sangli, Maharashtra, India-415404    ABSTRACT The phytoconstituents of the medicinal plants have been collected from the chemical database pubchem. 3-hydroxy-3-methylglutaryl-coenzyme A is the target for the docking analysis (HMG CoA reductase). Obesity refers to the accumulation of abnormal or

Molecular Docking Studies of Novel Morpholine Derivatives against SARS-CoV-2 Inhibitors for COVID-19

Akshay R. Yadav1*, Shital B. Khade2, Vaibhavi Annasaheb Soundatti3 1Assistant Professor, Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Dist- Sangli, Maharashtra, India-415404 2Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon, Dist- Sangli, Maharashtra, India-415404 3Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Kolhapur, Maharashtra, India-416013      ABSTRACT Morpholine is a heterocycle used

Toxicological Evaluation Using Brine Shrimp (Artemia salina L.) Model and Antimicrobial Potential of Barleria Prionitis leaf Extracts on Microorganism of Hospital Origin

Pravin P. Honmane*1, Akshay R. Yadav2, Santosh K. Singh3, Rajendra C. Doijad4, Shrinivas K. Mohite5 1,4Department of Pharmaceutical Chemistry, Krishna Institute of Pharmacy, Karad, Maharashtra, India-415539 2,5Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Sangli, Maharashtra, India-415404 3Suresh Gyan Vihar University, Jaipur, India-302025     ABSTRACT The present research is first to investigate at the antibacterial